Applying one-molecule optical and AFM imaging and pressure-spectroscopy tactics, we seek out to unravel the mechanistic elements of the structure and dynamics of chromosomes. Our investigate passions consist of:

Human Rad51 filaments on double- and single-stranded DNA: correlating common and irregular forms with recombination purpose.

Dynamics of initiation, termination and reinitiation of DNA translocation from the motor protein EcoR124I

Deposition and atomic drive microscopy of individual phthalocyanine polymers between nanofabricated electrodes

De sterke polarisatie in de discussie rond schepping/evolutie en meer algemeen rond geloof/wetenschap lijkt helaas geen eind te kennen. Toch is er wel degelijk een heilzame middenweg, maar deze krijgt in excess of het algemeen weinig aandacht. Dit boek kan hier wellicht verandering in brengen. Wie de geschiedenis van de relatie tussen geloof en wetenschap in duikt, komt tot verrassende inzichten. De moderne mens leeft satisfied veel stereotypen die historisch niet verantwoord blijken te zijn. Afgezaagde typeringen als ‘Vroeger dachten we dat de

Cornelis (Cees) Dekker (Haren, 7 april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en satisfied 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.

We use nanofabricated microfluidic structures to pattern spatial boundaries for bacteria and biomimetic vesicles with reconstituted protein networks which evaluate the elemental position of spatial confinement with the molecular and cellular degree. Our tasks contain the subsequent:

He also uncovered time to write down various books, send out Nearly forty thousand tweets and direct A prosperous analysis team at Delft College of Engineering. ‘It doesn’t experience like perform’, he suggests. ‘I’m just terribly curious.’

‘Sure, I fully grasp individuals ended up surprised at enough time. At the conclusion of the nineties, when I was in my forties, I used to be Professor of Molecular Electronics and I've to admit that it had become a little bit bored, I didn’t discover Considerably anymore. The field went far more into the applying side, how you might combine nanotubes into Digital circuits.

At this time, we also realized that it ought to be doable to employ one semiconducting carbon nanotube for making a transistor — and we established out to make it. We stretched person semiconducting nanotubes across metallic electrodes and utilized the underlying silicon substrate to be a gate electrode, creating The fundamental three-terminal layout of the subject-result transistor (Fig.

In 1993 he was appointed as Affiliate Professor at Delft College of Technological know-how. Inside the mid-nineties Dekker and his workforce accomplished results with the invention from the electronic Houses of carbon nanotubes, the first single-molecule transistor and also other nanoscience.

‘That considerations the artificial cell, as Component of the Dutch BaSyC initiative. Craig Venter looked prime-down in These times and discovered about five hundred genes that happen to be minimally necessary for just a working mobile. We wish to appear bottom-up: how can we move https://www.ceesdekker.net from a several molecules to an entire biological technique?

Enable’s first appear back in the intervening time after you decided to shift your concentrate from superconductivity and nanotubes to biology at the end of the 1990s.

Supercoiling-dependent DNA binding: quantitative modeling and programs to bulk and one-molecule experiments